ea0063p696 | Pituitary and Neuroendocrinology 2 | ECE2019
Garrahy Aoife
, Brady Zarina
, Sherlock Mark
, Thompson Christopher J
, Agha Amar
, Javadpour Mohsen
Transsphenoidal surgery (TSS) to resect a corticotroph adenoma is the first-line treatment for Cushings disease (CD); remission rates of up to 80% have been reported in cases of microadenomas. Endocrine Society guidelines define post-operative biochemical remission as morning serum cortisol <138 nmol/L within seven days of surgery. Our practice is to use a cut-off of <50 nmol/L at day 3 post-op to indicate biochemical remission. If serum cortisol on day 3 is 50&#...